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Splenic antibody-secreting cells are reduced in IκBNS KO mice. A) Immunoglobulin-secreting cells for WT and IκBNS KO mice were compared using an ELISPOT assay on total splenocytes after RBC lysis. The number of antibody secreting cells (ASC) per 106 spleen cells (B) and bone marrow cells (C) are shown graphically. Results are a compilation of three to five independent assays. Statistical analysis was performed using the Student's t-test.
