Table 1.
Treatment | Probands |
Relatives |
||
---|---|---|---|---|
Health States* | Utilities | Health States* | Utilities | |
Screening | Men and women who received false-negative screening result | 0.760 | ||
Germline testing | Men and women who declined germline testing | 0.660 | Men and women who declined germline testing | 0.719 |
Men and women who accepted germline testing, without Lynch syndrome | 0.760 | |||
Male relatives who accepted germline testing, with Lynch syndrome | 0.739 | |||
Germline testing and risk-reducing surgery | Men and women who accepted germline testing, with Lynch syndrome, and: | Female relatives who accepted germline testing, with Lynch syndrome, and: | ||
Declined TAH/BSO at age 40 years or colectomy at time of diagnosis | 0.622 | Declined TAH/BSO at age 40 years | 0.669 | |
Accepted TAH/BSO at age 40 years or colectomy at time of diagnosis | 0.672 | Accepted TAH/BSO at age 40 years | 0.697 | |
Cancer treatment | Colorectal cancer | 0.601 | Colorectal cancer | 0.601 |
Endometrial cancer | 0.728 | Endometrial cancer | 0.728 | |
Ovarian cancer | 0.593 | Ovarian cancer | 0.593 |
Abbreviation: TAH/BSO, total abdominal hysterectomy/oophorectomy.
Separate health states represented in the model by their own utility weight.