Table 1. Correlation between PDEF expression and Disease parameters.

PDEF expression or loss in patient samples was compared to uPA and MMP7 expression, node status and tumor differentiation using the χ² test. A statistically significant correlation is found between PDEF loss and uPA expression. Although, PDEF re-expression down-regulated MMP-7 mRNA levels in DLD-1 cells, there is not a statistically significant correlation between MMP-7 expression in tumor tissues and PDEF loss. No statistical significant correlation between PDEF loss and lymph node involvement or tumor differentiation.

		PDEF Expression
		Lost	Expressed	X2	P value
	NEG	5	4	6.6	0.01
uPA	POS	15	1
	NEG	7	2	0.043	0.8
MMP-7	POS	13	3
	NEG	9	3	0.157	0.6
Node Status	POS	9	2
	Well	2	2	2.8	0.2
Tumor	Moderate	9	1
Differentiation	Poor	9	2