Fig. 8.

HFOPs in the retinal model depend on gap junction-mediated excitation and axon-mediated inhibition. (a,b) Applying a weak full-field stimulus (intensity = 1/16) approximately doubled the level of synchrony between ganglion cell pairs at all separations relative to spontaneous levels (solid line, circles). (a) The increase in long-range synchrony produced by full-field stimulation could be reversed by reducing the coupling strength of the gap junctions from ganglion cells to axon-bearing amacrine cells by 25% (dashed line, squares). Reducing this coupling by 50% (dotted line, triangles) produced levels of long-range synchrony that were significantly below background. (b) Reducing axon-mediated inhibition of the ganglion cells by 25% (dashed line, squares) reduced the long-range synchrony evoked by full-field stimulation to near background levels. Reducing this axon-mediated inhibition by 50% (dotted line, triangles) reduced long-range synchrony to below background levels.