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. 2001 May 15;98(11):6447–6452. doi: 10.1073/pnas.111140398

Figure 2.

Figure 2

Percentage change (± SEM) in estimated testis volume over the 46-wk experiment for hamsters that had been treated with Mel- or beeswax-containing cannulas in the NRE, PVT, or SCN. All Mel-implanted groups exhibited at least a 30% reduction in ETV after week 6 and differed significantly from controls from week 4 to week 40 (P ≤ 0.001). Between week 22 and 28, testes of all Mel-implanted groups had increased in volume well above the minimum values attained ≈10 wk earlier. At week 40, all brain Mel implants were removed and replaced with beeswax implants. The arrow at week 40 depicts the onset of the s.c. Mel infusion. At week 46, after 6 wk of s.c. Mel infusions, all groups had similarly regressed gonads (P > 0.5).