Table 1.
P4 | P9 | P30 | |
---|---|---|---|
WT | 46.0 ± 0.5 | 19.2 ± 0.4 | 16.6 ± 0.3 |
β2−/− | 45.6 ± 0.2 | 39.6 ± 1.0* | 34.0 ± 1.3* |
Physiol. | 18.3 ± 0.6 | ||
Epib. | 40.0 ± 0.9*† |
Percentage of dLGN area occupied by ipsilateral fibers in wild-type (WT) and β2−/− mice at different postnatal ages, and in WT mice binocularly injected with 1 mM epibatidine (epib.) or physiological solution (physiol.) from P3 to P7 and analyzed at P9. Mean values ± SEM are shown. P4 (WT, n = 8; β2−/−, n = 6); P9 (WT, n = 6; β2−/−, n = 12; epib., n = 6; physiol., n = 6); P30 (WT, n = 10; β2−/−, n = 8). Statistical analysis according to one-way ANOVA followed by post hoc Fischer test for multiple comparisons (limited to P9): *, P < 0.0001 vs. WT; †, P < 0.0001 vs. physiol.