Table S1.
Domain combinations occurring most often in PFAM regarding sensor and response regulator proteins.
| Combination of sensor domains | Response regulator domains |
|---|---|
| HisKA + | HATPase_c + |
| (n * HAMP + m * | |
| PAS + p * Hpt)1 | |
| HATPase_c | Response_reg * s2 |
| HAMP | Response_reg + GerE |
| His_kinase + | Response_reg + HTH |
| HATPase_c | |
| HisKA + | Response_reg + LytTR |
| HATPase_c | |
| HWE_HK | Response_reg + HisKA domain |
| HisKA_2 + | Response_reg + CheB or CheW |
| HATPase_c | |
| HisKA_2 | Response_reg + Sigma |
| HisKA_3 | Response_reg + Spo |
| HisKA | Response_reg + GGDEF |
| Response_reg + EAL | |
| Response_reg + HDOD |
Notes: PFAM-family combinations in sensor and response regulator proteins are listed ordered by the frequency of occurrence (top ranked combination are shown at the top; however, each sensor domain combination can combine with any of the response domain combinations). Lower case letters symbolize domain replicates within a specific combination.
1
m: 0–6, n: 0–10, p: 1–9;
2
s: 1–2;