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. 2012 May 9;7(5):e36384. doi: 10.1371/journal.pone.0036384

Figure 3. Pooled siRNAs demonstrate greater knockdown efficacy than single siRNAs.

Figure 3

Comparison of the ability of transfected pooled vs. single siRNAs to A. knockdown target gene mRNA levels and B. reduce G6PC mRNA levels in AH-G6PC cells incubated with Dex/cAMP and 10 nM insulin for 6 h. Black bars are pooled siRNA samples; grey bars are single siRNA samples. Data are presented as fold changes relative to mRNA expression in siControl-transfected cells and are the means of 3 independent experiments for A and B.