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. Author manuscript; available in PMC: 2013 Jul 1.
Published in final edited form as: Glia. 2012 Apr 12;60(7):1106–1116. doi: 10.1002/glia.22338

Figure 3. Panx1 channels contribute to P2X7 receptor currents.

Figure 3

(A, B) Examples of BzATP-induced whole cell currents recorded from (A) Panx1+/+ and (B) Panx1−/− solitary astrocytes (holding potential of −60 mV). (C) Bar histograms of the mean ± s.e.m values of BzATP-induced currents recorded from solitary Panx1+/+ astrocytes in the absence and presence of MFQ (100 nM) and CBX (50 μM). Note that BzATP current amplitudes recorded from Panx1−/− astrocytes are quite similar to those recorded from Panx1+/+ in the presence of Panx1 channel blockers. **P<0.01 calculated from 4–6 independent recordings.