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. 2001 May 15;98(11):6459–6463. doi: 10.1073/pnas.111155398

Figure 2.

Figure 2

Modulation of ASIC and DRASIC by temperature. (A) Representative recordings of human ASIC and DRASIC proton-activated current (pH 5 and 4, respectively) in Xenopus oocytes at the indicated temperatures (−60 mV). (B) Arrhenius plot of the temperature dependence of the τ of DRASIC desensitization after activation by pH 4 (mean ± SEM, n = 6) and FaNaCh desensitization after activation by addition of 10 μM FMRFamide (mean ± SEM, n = 9 or 10). τ of desensitization was determined by single-exponential fits of the desensitization phase of the transient current.