Table 4.
Odds ratios (95% confidence intervals) obtained from GEE analysis for severe incontinence by each measure of BMI across the adult life
| BMI (kg/m2) | Age adjusted | p-value* | Fully adjusted§ | p-value* |
|---|---|---|---|---|
| Body mass index at 20 | 0.03 | 0.08 | ||
| BMI < 20 | 0.82 (0.51 - 1.30) | 0.87(0.54 - 1.39) | ||
| 20 ≤ BMI <25 | Reference | Reference | ||
| 25 ≤ BMI < 30 | 1.75 (0.992- 3.08) | 1.47 (0.81 - 2.67) | ||
| BMI ≥ 30 | 4.63 (2.04 - 10.46) | 3.29 (1.51 - 7.18) | ||
| BMI (per unit kg/m2) | 1.11 (1.06 - 1.17) | <0.0001 | 1.07 (1.03 - 1.12) | 0.001 |
| Body mass index at 26 | 0.0006 | 0.006 | ||
| BMI < 20 | 0.55 (0.32 - 0.95) | 0.59 (0.35 - 1.00) | ||
| 20 ≤ BMI <25 | Reference | Reference | ||
| 25 ≤ BMI < 30 | 1.81 (1.13 - 2.91) | 1.54 (0.95 - 2.50) | ||
| BMI ≥ 30 | 3.27 (1.53 - 7.00) | 2.53 (1.26 - 5.06) | ||
| BMI (per unit kg/m2) | 1.08 (1.05 - 1.12) | <0.0001 | 1.06 (1.03 - 1.10) | 0.001 |
| Body mass index at 36 | 0.0001 | 0.002 | ||
| BMI < 20 | 0.51 (0.26 - 1.02) | 0.54 (0.27 - 1.04) | ||
| 20 ≤ BMI <25 | Reference | Reference | ||
| 25 ≤ BMI < 30 | 1.76 (1.15 - 2.68) | 1.56 (0.99 -2.43) | ||
| BMI ≥ 30 | 2.86 (1.64 - 4.99) | 2.30 (1.33 -3.98) | ||
| BMI (per unit kg/m2) | 1.08 (1.04 - 1.11) | <0.0001 | 1.06 (1.03 - 1.10) | 0.001 |
| Body mass index at 43 | 0.0005 | 0.01 | ||
| BMI < 20 | 0.52 (0.20 - 1.35) | 0.63 (0.26 - 1.51) | ||
| 20 ≤ BMI <25 | Reference | Reference | ||
| 25 ≤ BMI < 30 | 1.42 (0.94 - 2.15) | 1.35 (0.88 - 2.09) | ||
| BMI ≥ 30 | 2.66 (1.67 - 4.22) | 2.11 (1.32 - 3.39) | ||
| BMI (per unit kg/m2) | 1.08 (1.04 - 1.11) | <0.0001 | 1.07 (1.03 - 1.10) | 0.0001 |
| BMI transition between 20 to 43 years |
0.002 | 0.02 | ||
| Always underweight/normal weight | Reference | Reference | ||
| Lost weight† | 2.61 (0.88 - 7.76) | 2.69 (0.76 - 9.55) | ||
| Gained weight‡ | 1.72 (1.14 - 2.60) | 1.60 (1.03 - 2.47) | ||
| Always overweight/obese | 3.14 (1.82 - 5.41) | 2.37 (1.38 - 4.06) | ||
| Age at onset of overweight/obesity |
0.004 | 0.05 | ||
| Always underweight/normal weight | Reference | Reference | ||
| Age 20 | 2.92 (1.74 - 4.89) | 2.30 (1.36 - 3.93) | ||
| Age 26 | 2.39 (1.37 - 4.18) | 1.93 (1.05 - 3.55) | ||
| Age 36 | 1.51 (0.87 - 2.61) | 1.34 (0.75 - 2.38) | ||
| Age 43 | 1.28 (0.73 - 2.25) | 1.25 (0.71 - 2.24) |
*
p-value corresponds to the test for heterogeneity across the categories;
§
adjusted for age, childhood enuresis, kidney infection, childbirth characteristics, menopausal status, GP consultations, and educational qualifications.
†
Decreasing at least one BMI category;
‡
increasing at least one BMI category.