Table 1.
Calculations used to derive the cost estimates for the different erythropoiesis-stimulating agents.
| Public pack price |
NHS price |
|||||
|---|---|---|---|---|---|---|
| Germany | France | Italy | Spain | UK | ||
| Price parity conversion (€/1000 IU) | ||||||
| Originator epoetin α 40,000 IU | 9.39 | 7.90 | 11.39 | 10.01 | 7.53 | |
| Epoetin β 30,000 IU | 9.42 | 8.19 | 12.42 | 9.55 | 7.96 | |
| Darbepoetin α 150 µg | 13.56 | 8.04 | 12.66 | 9.60 | 8.33 | |
| Biosimilar epoetin α 40,000 IU | 9.27 | 6.82 | 9.68 | 7.67 | 5.78 | |
| Germany | France | Italy | Spain | UK | G5 median | |
| Weekly price (€/1000 IU equivalent dose) | ||||||
| Originator epoetin α | 375.60 | 316.00 | 455.60 | 400.40 | 301.20 | 375.60 |
| Epoetin β | 376.80 | 327.60 | 496.80 | 382.00 | 318.40 | 376.80 |
| Darbepoetin α | 542.40 | 321.60 | 506.40 | 384.00 | 333.20 | 384.00 |
| Biosimilar epoetin α | 370.80 | 272.80 | 387.20 | 306.80 | 231.20 | 306.80 |
| Germany | France | Italy | Spain | UK | Weighted G5 | |
| Weighted weekly price* (€/1000 IU equivalent dose) | ||||||
| Originator epoetin α | 97.16 | 65.07 | 87.40 | 58.47 | 59.50 | 367.60 |
| Epoetin β | 97.47 | 67.46 | 95.30 | 55.79 | 62.90 | 378.91 |
| Darbepoetin α | 140.30 | 66.22 | 97.14 | 56.08 | 65.83 | 425.57 |
| Biosimilar epoetin α | 95.92 | 56.17 | 74.28 | 44.80 | 45.67 | 316.84 |
*
Weighted price per country is calculated by multiplying price per 1000 IU equivalent dose and proportional population weight.