Table 1. Descriptive statistics of patient-reported outcomes by time point and change in score.

	Year 5(during the fifth year on ET)				Year 6 (∼1 year after ceasing ET)				Change (year 6–year 5)
	N	Med	Min	Max	N	Med	Min	Max	Mean	Med	s.d.	Min	Max	Pa
CFQ	99	35.00	7.00	64.00	100	35.0	3.00	65.00	−1.10	−1.00	7.33	−27.00	14.00	0.25
BFI	98	1.61	0.00	7.44	98	2.11	0.00	8.44	0.17	0.28	1.77	−6.78	4.44	0.12
GHQ	100	0.00	0.00	10.00	99	0.00	0.00	10.00	0.13	0.00	2.38	−10.00	10.00	0.28
QOL indicators
Physical well-being	100	9.5	0	94	98	13.0	0	100	1.09	0.5	22.64	−79	99	0.45
Mood	100	8.0	0	97	98	12.0	0	100	1.45	0.0	20.69	−61	94	0.56
Tiredness	100	22.0	0	96	98	30.0	0	100	4.05	4.5	28.49	−80	76	0.09
Appetite	100	5.5	0	84	98	6.5	0	100	0.16	0.0	22.65	−72	99	0.70
Hot flushes	100	20.0	0	100	98	6.0	0	100	−10.3	−2.0	30.87	−99	100	0.0005
Feeling sick	100	2.0	0	77	98	1.0	0	100	−0.66	0.0	18.18	−76	100	0.32
Effort to cope	100	6.0	0	88	99	4.0	0	100	−2.44	−1.0	20.59	−88	100	0.12
Arm restriction	100	3.0	0	95	99	4.0	0	100	1.73	0.0	23.26	−76	100	0.38
Subjective health	100	10.0	0	86	98	11.0	0	100	0.14	0.0	20.53	−85	100	0.85

Abbreviations: ET=endocrine therapy; Med=median; Min=minimum; Max=maximum; CFQ=Cognitive Failure Questionnaire; BFI=Brief Fatigue Inventory; GHQ=General Health Questionnaire. For all outcomes, higher scores reflect a poorer condition, and a negative change indicates an improvement.

^aP-value calculated using the Wilcoxon signed-rank test.