Effects of ticlopidine and aspirin on serum VEGF (A) and
endostatin (B) levels. Beginning 3 days after ulcer
induction, rats were given vehicle, ticlopidine (300 mg/kg), or
aspirin (30 mg/kg) orally each day for 7 days. The “No
ulcer” group consisted of sham-operated rats that were treated each
day with vehicle. *, P < 0.05;
**, P < 0.01 vs. the corresponding
vehicle-treated group. #, P < 0.01 vs. the “No
ulcer” group.