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. 2012 Apr 19;2012:413196. doi: 10.1100/2012/413196

Table 1.

Effect of various fraction of ethanol extract of Stereospermum suaveolens on glucose level by acute treatment in STZ-induced diabetic rat.

Groups 0 h 1/2 h 1 h 2 h 4 h 5 h
Normal (5% DMSO in 0.9% NaCl, 5 mL /kg ) 84.16 ± 2.34 85.00 ± 2.68 87.73 ± 2.21 90.23 ± 2.05 89.13 ± 2.34 83.83 ± 2.44
STZ-induced diabetic control (40 mg/kg) 294.65 ± 1.86 a,∗∗ 300.21 ± 3.57a,∗∗ 302.25 ± 6.10a,∗∗ 298.16 ± 5.31a,∗∗ 299.56 ± 6.24a,∗∗ 305.16 ± 4.82a,∗∗
STZ+ Pet ether fraction (200 mg/kg) 284.04 ± 1.82 280.14 ± 5.76 265.16 ± 6.28b,∗ 256.53 ± 6.72b,∗∗ 248.83 ± 6.42b,∗ 234.71 ± 5.67b,∗∗
STZ + Chloroform fraction (200 mg/kg) 267.24 ± 1.46 262.63 ± 1.45 258.84 ± 2.18 254.5 ± 2.14 253.49 ± 2.81 261.24 ± 3.81
STZ + Ethyl acetate fraction (200 mg/kg) 264.81 ± 1.96 241.16 ± 4.54 229.23 ± 6.14b,∗∗ 212.38 ± 6.51b,∗∗ 197.67 ± 7.68b,∗∗ 187.28 ± 6.436b,∗∗
STZ + Aqueous fraction (200 mg/kg) 286.90 ± 2.31 285.09 ± 3.81 281.84 ± 2.18 279.30 ± 2.72 272.65 ± 2.73 279.50 ± 3.73
STZ + Glibenclamide (0.5 mg/kg) 286.50 ± 6.35 255.50 ± 8.08b,∗∗ 224.83 ± 7.18b,∗∗ 162.00 ± 7.81b,∗∗ 162.00 ± 7.81b,∗∗ 111.50 ± 7.13b,∗∗

Values are given as mean ± SEM, 6 rats in each group,

a, ∗∗ P < 0.001 as compared to normal control group,

b, ∗ P < 0.05, **P < 0.001, when compared with STZ-treated control group.