Table 3.
Effect of ethyl acetate fraction of Stereospermum suaveolens on body weight in STZ-induced diabetic rats.
| Groups | Body weight (g) | ||||
|---|---|---|---|---|---|
| 1st day | 4th day | 7th day | 10th day | 15th day | |
| Normal (5% DMSO in 0.9% NaCl, 5 mL/kg) | 185.73 ± 1.96 | 185.86 ± 1.32 | 196.00 ± 3.37 | 193.72 ± 3.24 | 197.26 ± 2.06 |
| STZ-induced diabetic control (40 mg/kg) | 181.25 ± 2.61 | 171.63 ± 2.70a, # | 164.81 ± 3.73a, # | 154.53 ± 2.74a, # | 154.13 ± 1.86a,# |
| STZ + Ethyl acetate fraction (200 mg/kg) | 182.60 ± 3.24 | 184.57 ± 0.64b,∗∗ | 189.12 ± 2.38b,∗∗ | 191.62 ± 2.29b,∗∗ | 194.57 ± 1.25b,∗∗ |
| STZ + Glibenclamide (0.5 mg/kg) | 184.06 ± 3.22 | 172.50 ± 0.84 | 169.13 ± 2.40 | 164.26 ± 2.21 | 159.56 ± 1.45 |
Values are mean ± SEM, 6 rats in each group,
a, # P < 0.001 as compared to normal control group,
b, ∗∗ P < 0.001, when compared with STZ-treated control group.