Table 3.
BP variability, instability, and mean levels of BP at baseline and 6 months after ablation.
Systolic BP |
Diastolic BP |
|||||
---|---|---|---|---|---|---|
Before renal denervation | 6 months follow-up | p-Value | Before renal denervation | 6 months follow-up | p-Value | |
BP VARIABILITY AND INSTABILITY (ABPM) | ||||||
Standard deviation, mmHg | ||||||
24 h | 16.9 ± 4.6 | 13.5 ± 2.5 | 0.003 | 11.2 ± 2.9 | 8.6 ± 1.9 | 0.007 |
Daytime (10 AM–8 PM) | 15.1 ± 4.1 | 11.7 ± 2.1 | 0.005 | 10.7 ± 3.5 | 7.5 ± 1.3 | 0.010 |
Night-time (12 AM–6 AM) | 12.7 ± 6.1 | 10.0 ± 4.4 | 0.365 | 9.1 ± 3.8 | 7.5 ± 3.1 | 0.175 |
Coefficient of variation | 0.11 ± 0.03 | 0.09 ± 0.02 | 0.041 | 0.14 ± 0.03 | 0.11 ± 0.02 | 0.024 |
Maximum (24 h), mmHg | 190 ± 22 | 172 ± 20 | <0.001 | 112 ± 25 | 98 ± 18 | 0.043 |
Δmax of consecutive readings (24 h), mmHg | 40 ± 15 | 28 ± 7 | 0.006 | 37 ± 11 | 20 ± 5 | 0.011 |
Maximum increase from 4 AM to 10 AM, mmHg | 53 ± 19 | 40 ± 17 | 0.058 | 32 ± 20 | 25 ± 11 | 0.035 |
MEAN LEVELS (OFFICE AND ABPM) | ||||||
Office BP, mmHg | 189 ± 23 | 158 ± 24 | 0.007 | 92 ± 15 | 88 ± 17 | 0.648 |
Mean ABPM, mmHg | ||||||
24 h | 149 ± 19 | 142 ± 18 | 0.086 | 82 ± 17 | 79 ± 15 | 0.167 |
Daytime (10 AM–8 PM) | 155 ± 22 | 145 ± 22 | 0.083 | 85 ± 17 | 81 ± 16 | 0.206 |
Night-time (12 AM–6 AM) | 137 ± 17 | 136 ± 16 | 0.966 | 74 ± 15 | 74 ± 14 | 0.781 |
ABPM, ambulatory blood pressure monitoring; BP, blood pressure.