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. 2012 Apr;14(4):344–351. doi: 10.1593/neo.12446

Figure 2.

Figure 2

3D telomere organization in interphase nuclei. (A) Nucleus from the [T38HxBALB/c]N wild-type mouse. (B) Nucleus from the [T38HxBALB/c]N with rcpT(X;11) mouse. (C) Nucleus from the fast-onset PCT mouse. (D) Comparison of the telomeric profile of the three mouse types. The intensity correlates to the telomere length. The fast-onset PCT nuclei (black) have significantly more very short telomeres (see Materials and Methods) than the [T38HxBALB/c]N wild-type (red) and the [T38HxBALB/c]N with rcpT(X;11) (blue) mouse (P =.006 and P < .0001, respectively).