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Oxidized SP-B does not inhibit sPLA2 hydrolysis of surfactant. Surfactant PL hydrolysis was measured for vesicles using 10 U of Group IB sPLA2 and the PL mix described in as in Fig. 2. Shown are 3 conditions, without SP-B (0 SP-B), with 1% SP-B, and with 1% oxidized SP-B (1%H-SP-B). *P < 0.02 vs. enzyme alone.
