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Effects of K252a on the change of pulmonary resistance (RL) and dynamic compliance (Cdyn) to methacholine (MCh) in PD2–11 of FA (opened bar)- or SS (closed bar)-exposed mice. A: pretreatment with vehicle (2% DMSO in normal saline solution). B: pretreatment with K252a. C: pretreatment with IgG. D: pretreatment with NGF antibody. Values are means ± SE; n = 5. *P ≤ 0.05, significant difference between FA- and SS-exposed mice.
