Fig. 8.

Comparison of (A) ANG II-induced contractions by denuded third generation uterine (■, n = 6) and carotid (□, n = 4) arteries from term pregnant sheep and the effects of receptor subtype inhibition with losartan (LOS) or PD123,319 (PD) on carotid responses to ANG II and (B) AT₁R and AT₂R subtype expression in uterine (n = 5, ■) and carotid (n = 5, □) vascular smooth muscle. Immunoblots and summary data for densitometry are presented. *P = 0.01 compared with uterine artery. Different letters represent significant differences by ANOVA, P = 0.002, for comparison of responses to ANG II after ATR subtype inhibition. Data are means ± SE.