Fig. 1.

Renal cortical NADPH oxidase enzymatic activity (A) and basal cortical O₂⁻ production (B) in untreated and ANG II-treated male (M) and female (F) spontaneously hypertensive rats, as measured by lucigenin chemiluminescence. C: nitrotyrosine content was measured in the renal cortex as an oxidative stress marker by slot blot analysis; n = 5–6.