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Effect of apocynin on ANG II hypertension. Twenty-four-hour mean arterial pressure (MAP) was measured by telemetry and in male and female SHR. Apocynin treatment was begun on day 8 with ANG II infusion initiated on day 15 in male (A) and female SHR (B). #Significant difference from untreated, P < 0.05. *Significant difference from same-sex baseline blood pressure, P < 0.05; n = 4 or 5.
