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. 2011 Oct 26;302(2):R264–R273. doi: 10.1152/ajpregu.00114.2011

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Fig. 6. — Gene transcript levels in brain and nodose ganglia of capsaicin- and vehicle-treated rats measured by quantitative real-time PCR. A: hypothalamic expression of mRNAs coding for GLP-1R, NPY, and POMC in capsaicin-treated (n = 8) and vehicle-treated rats (n = 8). B: hindbrain expression of mRNAs coding for GLP-1R and TH in capsaicin-treated (n = 9) and vehicle-treated rats (n = 9). C: expression of GLP-1R and CCK-1R mRNA in nodose ganglia from capsaicin-treated (n = 7) and vehicle-treated rats (n = 7). Expression of cyclophilin A mRNA was used as a reference transcript, and the expression of other genes was calculated as a ratio to cyclophilin A mRNA. Expressions of GLP-1R, NPY, and POMC genes in the hypothalamus did not differ between capsaicin-treated and vehicle-treated rats (P > 0.1). Expression of both GLP-1R and TH genes in the hindbrain also did not differ between capsaicin-treated and vehicle-treated rats (P > 0.1). In the nodose ganglia, CCK-1R expression was comparable in capsaicin-treated rats and vehicle-treated rats (P > 0.1), while GLP-1R expression was decreased in capsaicin-treated rats (*P < 0.05).