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GTPase enzymatic activity in cortical tissues from cortical tissues from the APP (n = 6), APP/PS1 mice (n = 6), 3XTg.AD mice (n = 5) and WT mice (n = 6). GTPase enzymatic activity was significantly increased in the APP, APP/PS1 mice and 3XTg.AD mice relative to WT, non-transgenic mice.
