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. 2012 May 2;95(6):1454–1460. doi: 10.3945/ajcn.111.032698

TABLE 3.

Type 2 diabetes according to plain-water intake in the 4-y lagged analysis: stratified analyses1

Plain-water consumption
<1 cup/d 1 cup/d 2–3 cups/d 4–5 cups/d ≥6 cups/d P-linear trend
Stratified by BMI
 <30 kg/m2 (661 cases) 1.00 1.03 (0.82, 1.30) 0.95 (0.76, 1.19) 0.95 (0.72, 1.24) 1.09 (0.80, 1.49) 0.66
 ≥30 kg/m2 (2057 cases) 1.00 0.92 (0.79, 1.06) 0.93 (0.81, 1.06) 1.12 (0.97, 1.30) 1.01 (0.85, 1.19) 0.21
Stratified by physical activity level
 <9 MET-h2/wk (1411 cases) 1.00 0.83 (0.71, 0.98) 0.90 (0.78, 1.05) 1.11 (0.93, 1.32) 1.04 (0.84, 1.29) 0.27
 ≥9 MET-h/wk (1106 cases) 1.00 1.11 (0.89, 1.38) 1.11 (0.91, 1.35) 1.21 (0.97, 1.50) 1.23 (0.97, 1.55) 0.10
Stratified by hypertension
 Yes (1080 cases) 1.00 0.85 (0.70, 1.04) 0.82 (0.69, 0.99) 0.99 (0.81, 1.22) 1.01 (0.80, 1.27) 0.72
 No (1638 cases) 1.00 0.99 (0.84, 1.16) 0.98 (0.85, 1.13) 1.14 (0.97, 1.35) 1.03 (0.85, 1.25) 0.33
Stratified by high cholesterol
 Yes (1247 cases) 1.00 1.03 (0.86, 1.24) 1.06 (0.89, 1.25) 1.10 (0.90, 1.34) 1.21 (0.97, 1.51) 0.07
 No (1471 cases) 1.00 0.86 (0.73, 1.01) 0.84 (0.72, 0.98) 1.08 (0.91, 1.29) 0.96 (0.78, 1.17) 0.78
1

All values are RRs; 95% CIs in parentheses. Models were adjusted for age, race, family history of diabetes, BMI (in kg/m2) categories (<23.0, 23.0–24.9, 25.0–29.9, 30.0–34.9, or ≥35.0, but a continuous variable in the stratified analysis by BMI), smoking status (never, past, or current (1–14, 15–24, or ≥25 cigarettes/d)], alcohol intake (never or <5.0, 5.0–15.0, or ≥15.0 g/d), menopausal status and hormone use, oral contraceptive use, physical activity level (<3.0, 3.0–8.9, 9.0–17.9, 18.0–26.9, or ≥27.0 metabolic equivalent task hours per week, but a continuous variable in the stratified analysis by physical activity level), and the Alternative Healthy Eating Index (quintiles). None of the interaction tests were significant (all P-interaction > 0.10). P-linear trend was calculated by treating plain-water intake as a continuous variable.

2

Thirty-five women were excluded from the analysis because of missing values for physical activity level. MET-h, metabolic equivalent task hours.

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