Table 1.
Patient characteristics of leukemia samples xenografted in NOD/SCID mice
| Sample | Isolated from |
Type of leukemia |
Age (years) |
Gender | State of disease |
Cytogenetic characteristics |
|---|---|---|---|---|---|---|
| ALL-50 | PB | pre-B-ALL | 7 | f | ID | n.a. |
| ALL-53 | BM | pre-B-ALL | 14 | f | R | n.a. |
| ALL-54 | BM | pre-B-ALL | 3 | f | ID | not aberrant |
| ALL-177 | BM | pre-B-ALL | 8 | f | ID | TEL/AML1; del12p |
| ALL-199 | BM | pre-B-ALL | 8 | f | R | trisomy 21 |
| ALL-10S | BM | pre-B-ALL | 4 | f | ID | MLL-AF9 rearrangement |
| ALL-188 | BM | pre-B-ALL | 9 | f | ID | TEL/AML1 |
| ALL-4S | PB | T-ALL | 4 | m | ID | t(11;14);(p32;q11) |
| ALL-202 | PB | T-ALL | 9 | m | ID | del9p |
| ALL-168 | BM | pre-B-ALL | 5 | f | ID | der(19)t(1;19)(q23;p13) |
| ALL-169 | BM | pre-B-ALL | 18 | f | ID | n.a. |
PB peripheral blood, BM bone marrow, (pre-)B-ALL (precursor) B-cell acute lymphoblastic leukemia, T-ALL T-cell acute lymphoblastic leukemia, f female, m male, ID initial diagnosis, R relapse, n.a. no data available