Table 3.
Multivariate analysis of the association between prognosis and various clinicopathologic parameters in patients with PGC
| Features | Overall survival | Disease-free survival | ||||
|---|---|---|---|---|---|---|
| Hazard ratio | 95% CI | P | Hazard ratio | 95% CI | P | |
| Pathologic T stage (T1± T2 vs. T3 ± T4) | 0.528 | 0.106-5.291 | NS | 1.066 | 0.281-6.893 | NS |
| Clinical stage (I± II vs. III ± IV) | 8.862 | 1.328-26.523 | 0.008 | 3.391 | 1.183-9.923 | 0.02 |
| Nodal metastasis (Negative vs. Positive) | 1.728 | 0.553-6.965 | NS | 1.625 | 0.685-7.097 | NS |
| Distant metastasis (Negative vs. Positive) | 1.763 | 1.128-6.553 | NS | 1.711 | 0.737-7.267 | NS |
| Venous/lymphatic invasion (Negative vs. Positive) | 2.181 | 1.018-8.106 | NS | 2.527 | 1.023-8.298 | NS |
| Perineural invasion (Negative vs. Positive) | 0.826 | 0.115-3.089 | NS | 0.908 | 0.259-3.765 | NS |
| SOX4 expression (Negative vs. Positive) | 3.682 | 1.102-10.282 | 0.03 | 2.215 | 1.088-7.016 | 0.04 |
Note: 'NS' refers to 'No statistic significance'