Table 1. Cross-resistance between arsenic trioxide and other arsenic compounds in the NCI cell line panel.
free As2O3 | formulated As2O3 | |
formulated As2O3 | 4.14×10−14* | N/A |
potassium arsenite (KAsO2) | 1.76×10−12* | 2.51×10−9* |
dihydro-1,3,2-dithiarsenol-2-ylmercapto-acetic acid | 0.04565* | n.s. |
Log10 IC50 values obtained from SRB assays have been subjected to Pearson’s correlation test.
N/A, not applicable; N.S. not significant (P>0.05). * denotes significant correlation.