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. 2012 May 10;7(5):e35584. doi: 10.1371/journal.pone.0035584

Table 2. Separation of clusters of the NCI cell line panel obtained by the hierarchical cluster analysis shown in Figure 3 in comparison to drug sensitivity.

Partitiona Cluster 1 Cluster 2 Cluster 3 Chi2 Test
formulated arsenic trioxide sensitive ≤−5.346 2 22 6
resistant >−5.346 20 10 0 3.32635×10−6
free arsenic trioxide sensitive ≤−5.467 2 21 6
resistant >−5.467 20 10 0 4.50505×10−6
a

The median log10IC50 value (M) for each drug was used as a cut-off to separate tumor cell lines as being "sensitive" or "resistant".