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. 2011 Oct 19;107(1):484–492. doi: 10.1152/jn.00714.2011

Fig. 1.

Fig. 1.

Wild-type (wt) and superoxide dismutase 1 mutant (SOD1) current-voltage (IV) relationships. A: TTX-insensitive (TTX-ins) currents for both a wt (black) and a SOD1 (blue) neuron. Note that the SOD1 TTX-ins current has a more depolarized voltage onset and smaller amplitude. B: comparison of the persistent inward current (PIC) traces for the same wt (black, trace 1) and SOD1 (blue, trace 2) neurons as in A. Compare to the TTX-ins traces from the wt (light gray, trace 3) and SOD1 (light blue, trace 4). C: sodium PIC (NaPIC) for the same neurons: wt NaPIC (from B: trace 1 − trace 3). and SOD1 NaPIC (from B: trace 2 − trace 4). Note that the NaPIC amplitudes are nearly identical.