Table 3. Effect of treatment on static and dynamic histomorphometric indices in the trabecular region of the proximal tibia metaphysis in the treated leg.
| Treatment | sLS/BS | dLS/BS | MS/BS | MAR | BFR/BS |
| (%) | (%) | (%) | (μm/d) | (μm3/μm2/y) | |
| BTX-VIB | 19.4±15.2 | 5.6±4.4a | 15.3±9.2a | 1.33±0.25 | 70.2±35.7a,b |
| BTX-SHAM | 15.4±2.4 | 7.4±4.8b | 15.1±4.8 | 1.32±0.17 | 73.2±25.0 |
| VIB | 28.1±11.2 | 16.2±9.7 | 30.3±14.5 | 1.32±0.28 | 150.6±83.0 |
| SHAM | 20.7±5.9 | 17.8±8.4 | 28.2±8.7 | 1.49±0.21 | 152.0±50.7 |
a
Group is significantly lower than treated VIB leg (p<0.05); b Group is significantly lower than treated SHAM leg (p<0.01). Values are the mean ± SD (n = 8 for BTX-VIB and SHAM; n = 6 for BTX; n = 7 for VIB). Four samples were excluded due to processing errors. Samples (n = 3) without double labels were also excluded. sLS/BS = % single-labelled surface; dLS/BS = % double labelled surface; MS/BS = % mineralizing surface; MAR = mineral apposition rate; BFR/BS = bone formation rate, normalized by bone surface.