Receiver operating characteristics (ROC) curves searching for the utility of sbT levels for the identification of patients with grade ≥2 (panel A), grade 4 (panel B) disease and those who needed to be treated in an intensive care unit (panel C). The optimal sbT cutoff values detected in each case were of 6.6 µg/l (panel A), 16 µg/l (panel B), and 31 µg/l (panel C). AUC, area under the curve; CI, confidence interval.