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. Author manuscript; available in PMC: 2013 May 10.
Published in final edited form as: J Med Chem. 2012 Apr 20;55(9):4159–4168. doi: 10.1021/jm201609k

Figure 2.

Figure 2

Agonist and antagonist activities of selected peptides. Agonist activity was measured for peptides SQ110-4 and SQ060-4 (A) and SQ007-5 and SQ002-5 (B). Dibutyryl cAMP differentiated U937 cells were treated with the peptides of interest and receptor activation measured by intracellular calcium mobilization. Following treatment with peptides SQ007-5 and SQ002-5, 10 μM of the C3aR agonist, FLPLAR, was added and antagonist activity of the peptides measured (C). Data is displayed as the mean ± SEM. n = 3–6.