Visualization of the BOLD effect in raw, manually windowed, and images processed using ARREAS approach obtained from a canine at various physiological states (rest, stress, and stress with critical LAD stenosis) at end systole. The top panel shows the raw images. The middle panel shows the same images after they have been manually windowed. Note that myocardial oxygen deficit appears in these images in the affected (LAD) territory as regions of hypointensity. The bottom panel shows the raw images that have a color overlay (generated by ARREAS) permitting automatic depiction of the affected territory. The corresponding Affected Fraction (AF) values are 0.035, 0.002, 0.18, for rest, stress, and critical stenosis conditions. Observe the close correspondence between the automatically detected (colored) and the hypointense regions on the windowed images, particularly in the LAD territory.