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. Author manuscript; available in PMC: 2013 May 1.
Published in final edited form as: Nutr Cancer. 2012 Apr 6;64(4):493–502. doi: 10.1080/01635581.2012.667862

Fig. 3. Effects of resveratrol on the NF-κB signaling pathway.

Fig. 3

Activation by cytokine results in IKK phosphorylation of IκBα, resulting in IκBα degradation, and facilitation of NF-κB nuclear translocation and subsequent activation of transcription (49). Resveratrol is demonstrated it inhibit NF-κB signaling at all steps (see text for references).