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. 2012 Feb;180(2):575–582. doi: 10.1016/j.ajpath.2011.10.032

Figure 1.

Figure 1

Decreased liver:body weight in myostatin-null mice. A: Percent liver:body weight ratio in 3-month-old wild-type, heterozygous (Het), and null mice (Male: *P < 0.001 versus wild-type; P = 0.002 versus Het; Female: **P = 0.002 versus wild-type; P = 0.03 versus Het). B: Liver weight in 3-month-old mice (no significant difference across groups). C: Body weight in 3-month-old mice (Male: *P < 0.001 versus wild-type; P = 0.001 versus Het; Female: **P = 0.002 versus wild-type; P = 0.02 versus Het). D: Liver weight, body weight, and liver:body weight ratio in 1-month-old male wild-type and null mice (no significant difference across groups). E: Total hepatic tissue alanine aminotransferase (ALT) activity:body weight ratio in 3-month-old mice. *P = 0.043 versus Het; *P < 0.001 versus wild type; **P < 0.005 versus wild type.