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. 2012 Feb;180(2):575–582. doi: 10.1016/j.ajpath.2011.10.032

Figure 6.

Figure 6

The hepatic regenerative response to partial hepatectomy in myostatin-null mice. A: Immunohistochemical analysis of hepatocellular BrdU incorporation 36 hours after partial hepatectomy, and H&E staining of liver 48 hours after partial hepatectomy (PH) (100 micron bar shown in BrdU stained wild-type liver section). B: Quantitative summary of hepatocellular BrdU incorporation 36 and 48 hours after partial hepatectomy and mitotic frequency (per 10 ×400 high-powered-fields) (HPF) 48 hours after partial hepatectomy in 3-month-old wild-type, heterozygous (Het), and myostatin-null mice (no significant differences across groups). C: Liver:body weight ratio at 72 hours and 7 days after partial hepatectomy in myostatin-null mice and heterozygous controls.