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. 2012 Apr;180(4):1474–1484. doi: 10.1016/j.ajpath.2011.12.032

Figure 2.

Figure 2

Effect of AIB1/SRC-3 on angiogenesis. Neoangiogenesis in subcutaneous Matrigel plugs injected subcutaneously into AIB1/SRC-3+/+, +/−, or −/− mice was monitored. A: Representative H&E-stained cross sections at ×4 (left of each pair) and ×10 (right of each pair) magnification of Matrigel plugs without (top row) and with FGF2 added (10 μg/mL) 5 days after implantation (bottom row). Scale bars: 0.25 mm. B: Number of endothelial cell nuclei in the plugs from 10 high-power fields per plug. Values are given as the mean ± SEM (n = 3 to 5 animals per group). *P < 0.0001 versus AIB1/SRC-3+/+; ns, P > 0.05 AIB1/SRC-3+/− versus −/−.