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. Author manuscript; available in PMC: 2013 Feb 8.
Published in final edited form as: Nano Lett. 2012 Jan 27;12(2):1038–1044. doi: 10.1021/nl204273h

Figure 2.

Figure 2

Experiments showing the slowing down of DNA translocation in LiCl. (a) Example current recordings for 48.5 kbp λ-dsDNA filtered at 5 kHz in 1 M KCl (left), 1 M NaCl (middle) and 1 M LiCl (right). (b) Same for 1 M LiCl, 2 M LiCl and 4 M LiCl. (c) Same for heat-shocked M13mp18 ssDNA in an additional 8 M Urea, filtered at 30 kHz. (d-f) Translocation time histograms corresponding to (a–c). For the dsDNA we find translocation times of τ = 1.72 ± 0.29 ms, 2.94 ± 0.55 ms, 8.23 ± 1.43 ms, 12.1 ± 1.9 ms, and 16.5 ± 2.2 ms in 1 M KCl, 1 M NaCl, 1 M LiCl, 2 M LiCl, and 4 M LiCl respectively. For the ssDNA we find translocation times of τ = 52 ± 10 μs, 71 ± 13 μs, and 530 ± 190 μs in 1 M KCl, NaCl, and LiCl respectively.