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. Author manuscript; available in PMC: 2012 Nov 1.
Published in final edited form as: Pharmacogenet Genomics. 2011 Nov;21(11):769–772. doi: 10.1097/FPC.0b013e328346063f

Table 1.

Pharmacogenomic associations of genetic variants in pharmacokinetic genes involved in the metabolism of citalopram

Gene Variant Phenotype References
ABCB1 rs2032583 Diminished efficacy of citalopram [33,34]
No effect on efficacy of citalopram [35]
ABCC1 rs2230671 Associated with remission state at 8-week citalopram treatment [36]
CYP2C19 *2 (rs4244285) Associated with lower odds of tolerance [52]
No association with antidepressant response [35]
CYP2C19 *17 (rs12248560) Trend of association of lower remission [52]
No association with antidepressant response [35]