Table 1.

Cardiac measurements in WT and CypD^–/– mice assessed at 2 and 28 days following sham surgery or MI

2 days	Sham		MI
	WT	CypD–/–	WT	CypD–/–
n number	3	4	11	10
Heart rate (bpm)	564.1 ± 26.8	565.6 ± 9.1	552.5 ± 20.1	554.3 ± 16.7
LVEDD (cm)	0.37 ± 0.03	0.35 ± 0.01	0.40 ± 0.01	0.41 ± 0.02
LVESD (cm)	0.24 ± 0.02	0.23 ± 0.01	0.30 ± 0.01	0.28 ± 0.02
FS (%)	35.8 ± 1.4	33.7 ± 1.4	24.8 ± 1.0*	31.8 ± 1.9†
EF (%)	71.6 ± 1.4	70.2 ± 1.4	55.8 ± 1.6*	66.4 ± 2.5†
28 days	Sham		MI
	WT	CypD–/–	WT	CypD–/–
n number	7	7	10	10
Body weight, BW (g)	28.2 ± 0.5	28.4 ± 0.3	29.6 ± 0.6	27.3 ± 0.7†
Heart weight, HW (mg)	153.2 ± 4.9	163.2 ± 4.9	250.5 ± 16.4*	223.4 ± 10.1*
HW/BW (mg/g)	5.44 ± 0.2	5.7 ± 0.2	8.4 ± 0.4*	8.2 ± 0.4*
Heart rate (bpm)	550.7 ± 24.3	485.4 ± 26.6	501.7 ± 21.4	497.1 ± 21.0
LVEDD (cm)	0.38 ± 0.02	0.38 ± 0.02	0.47 ± 0.02*	0.40 ± 0.02
LVESD (cm)	0.25 ± 0.02	0.24 ± 0.01	0.39 ± 0.02*	0.30 ± 0.02†
FS (%)	34.3 ± 3.1	36.0 ± 2.0	17.8 ± 1.3*	26.8 ± 1.8*†
EF (%)	69.1 ± 4.1	72.4 ± 2.3	41.0 ± 2.8*	58.0 ± 2.8*†

LVEDD: left ventricular end-diastolic diameter; LVESD: left ventricular end-systolic diameter; FS: fractioning shortening; EF: ejection fraction.

^*P < 0.05 versus respective sham, ^†P <0.05 versus MI WT.