Table 3.
Retrospective clinical scoring before and after rituximab administration
| Parameter (values assigned) | Patient 1 |
Patient 2 |
Patient 3 |
Patient 4 |
||||
|---|---|---|---|---|---|---|---|---|
| Before | After | Before | After | Before | After | Before | After | |
| Constitutional (fever, weight loss, malaise: 1 point each) | 0 (unknown) | 0 | 2 (fever, malaise) | 0 | 2 (fever, weight loss) | 0 | 2 (weight loss, malaise) | 0 |
| Clinical infection (0, healing of sinus tract; 1, stable lesion; 2, development of sinus tract) | 2 | 0 | 0 | 0 | 2 | 0 | 2 | 0 |
| Positive blood cultures (0, negative; 2, positive) | 2 | 0 | 2 | 0 | 0 | 0 | 0 | 0 |
| Radiographic change (0, resolved; 1, improvement; 2, stable; 3, progression) | 3 | 1 | 3 | 1 | 3 | 1 | 3 | 1 |
| Hypergammaglobulinemia (0, normal; 1, elevated) | 1 | 0 | 1 | 0 | 1 | 0 | 1 | 0 |
| Total score | 8 | 1 | 8 | 1 | 8 | 1 | 8 | 1 |