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Preintrapulmonary infection slightly prolongs the survival of mice subsequently infected with R265 via i.v. inoculation. Five to eight BALB/c mice per group were used. Mice were first inoculated i.p. with approximately 50 cells of H99 or R265. After 2 weeks, the preinfected and naive mice were injected i.v. with approximately 500 or 5,000 cells of H99 or R265. The survival of the mice was recorded.
