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Role of endogenous IP-10 in the activation of HCV replication regulated by HIV-1 Tat protein determined by antibody depletion. Huh7.5.1 cells were infected with FL-J6/JFH-5'C19Rluc2Aubi virus and then incubated with PBS, Tat, Tat plus MSIgG, and Tat plus anti-IP-10 neutralizing antibody, respectively, in 24-well plates for 120 h. Cells were then harvested at different times (as indicated) and luciferase activity was assayed.
