Table 2. Estimated CYP2E1 haplotype frequencies and p values among cases and controls.
Haplotype (rs3813867-rs2031920-rs2031921-rs3813870-rs2031922) | Case Frequency (%) | Control Frequency (%) | p value | Permutation p value | OR [95% CI] |
C T C A C | 15.5 | 19.3 | 0.0662 | 0.5671 | 0.742 [0.540–1.021] |
G C T A T | 56.6 | 58.7 | 0.2116 | 0.9955 | 0.856 [0.671–1.092] |
G C T G T | 18.0 | 18.1 | 0.7795 | 1.0000 | 0.957 [0.701–1.305] |
G T C A C | 9.7 | 0.9 | 7.47E-12 | <0.0001 | 11.348 [4.811–26.767] |
Global | 1.19E-10 | <0.0001 |
Only haplotypes with a frequency higher than 3% are listed.
OR: Odds ratio; CI: confidence interval.