Table 1. Characteristics of study population.
Measured at study initiation | |
n, subjects | 250 |
Sex (% male) | 32 |
Race (% white) | 59 |
Age (years) | 37.6 (12.5) |
Age of asthma onset (years) | 15.4 (14.7) |
Asthma duration (years) | 22.2 (12.2) |
BMI (kg/m2) | 29.9 (8.3) |
FEV1 (L) | 2.8 (0.8) |
FVC (L) | 3.9 (1.1) |
FEV1/FVC (%) | 71.8 (8.7) |
FEV1 (% predicted) | 82.2 (13.8) |
PC20 (mg/mL)† | 1.2 (1.2) |
Asthma Evaluation Questionnaire Score | 0.7 (0.8) |
Measured after 2 weeks HFA-BDP | |
Asthma Control Questionnaire Score | 1.0 (0.8) |
IgE (IU/mL) † | 105.4 (1.6) |
hsCRP (mg/L )† | 1.8 (1.4) |
Interleukin-6 (pg/mL)† | 1.4 (0.9) |
TNFα(pg/mL)† | 1.7 (0.8) |
Adiponectin (mcg/mL)† | 7.0 (0.7) |
Leptin (ng/mL)† | 10.8 (1.3) |
Measured after 4 weeks HFA-BDP | |
FENO (ppb) † | 19.9 (0.6) |
Sputum eosinophils (%) † | 0.8 (1.0) |
Asthma Evaluation Questionnaire Score | 0.6 (0.7) |
Asthma Control Questionnaire Score | 0.9 (0.8) |
Numeric data presented as mean (standard deviation), except †geometric mean (coefficient of variation), log-transformed for analysis.