Table 1. Cohorts characteristics and Post-1993 Subset from YTMA-130.
| Characteristic | YTMA 128 | YTMA 130 | YTMA 130 Subset | |
| No. (%) | No. (%) | No. (%) | p-value | |
| All patients | 238 | 524 | 226 | |
| Age, years | ||||
| <50 | 75 (31.5) | 152 (29.0) | 73 (32.3) | |
| ≥50 | 147 (61.8) | 293 (55.9) | 153 (67.7) | 0.3151 |
| Unknown | 16 (6.7) | 79 (15.1) | 0 (0) | |
| Nodal status | ||||
| Positive | 72 (30.3) | 72 (13.7) | 42 (18.6) | |
| Negative | 151 (63.4) | 253 (48.3) | 146 (64.6) | 0.4804 |
| Unsampled/unknown | 15 (6.3) | 199 (38.0) | 38 (16.8) | |
| Tumor size | ||||
| <2 cm | 143 (60.1) | 267 (51.0) | 145 (64.2) | |
| 2–5 cm | 72 (30.3) | 124 (23.7) | 69 (30.5) | 0.4469 |
| >5 cm | 10 (4.2) | 2 (0.4) | 0 (0) | |
| Unknown | 13 (5.5) | 131 (25.0) | 12 (5.3) | |
| ER (IHC) | ||||
| Positive (1–3) | 162 (68.1) | 220 (42.0) | 125 (53.3) | |
| Negative (0) | 39 (16.4) | 169 (32.3) | 87 (38.5) | 0.4823 |
| Unknown | 37 (15.5) | 135 (25.8) | 14 (6.2) | |
| PgR (IHC) | ||||
| Positive (1–3) | 142 (59.7) | 37 (7.1) | 28 (12.4) | |
| Negative (0) | 59 (24.8) | 349 (66.6) | 182 (80.5) | 0.0804 |
| Unknown | 37 (15.5) | 138 (23.3) | 16 (7.1) | |
| Her2 (IHC) | ||||
| Positive (2–3) | 56 (23.5) | 39 (7.4) | 26 (11.5) | |
| Negative (0–1) | 140 (58.8) | 344 (65.6) | 186 (82.3) | 0.2179 |
| Unknown | 42 (17.6) | 141 (26.9) | 14 (6.2) | |
| Follow-up, months | ||||
| Median | 49 | 81 | 64.5 | |
| Range | 1–340 | 2–327 | 3–169 | |
Abbreviations: ER, estrogen receptor; IHC, immunohistochemistry; PgR, progesterone receptor; YTMA, Yale tissue microarray (cohort).