Figure 3. Counter-regulated network signature in fat.

A) Interactive Network of top 20 focus gene hubs. B) Ranked list of top 20 focus gene hubs on the basis of degree of connectivity. The interactive network based analysis on the 238 fat counter-regulated genes identified 5 significant networks (Score≥40) related to cell cycle, lipid metabolism and carbohydrate metabolism. The merged network was generated from the top 3 networks of genes counter-regulated in fat by AAT and PM treatment. The focus gene hubs were ranked in the merged network on the basis of degree of connectivity.