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CHIP HET mice exhibit a significant decrease in motor stereotypies within an open field apparatus (B), but only a non-significant trend in total ambulatory distance (panel A, p = .135). However, upon separation of the open field into center and surround zones, there is a significant decrease in distance (C) and time spent in the center (D), suggesting an increase in anxiety-related behavior. *p<0.05, **p<0.01.
